Red Tart Cherry Extract — Red tart cherries are one of the few natural food sources of melatonin precursors. Research shows that tart cherry extract can increase melatonin availability in the body, helping to regulate the sleep-wake cycle, reduce nighttime awakenings, and increase total sleep time. It is also rich in antioxidants that support overnight cellular recovery.
5-HTP (5-Hydroxytryptophan) — 5-HTP is a naturally occurring amino acid and chemical precursor to serotonin. By supporting serotonin production in the brain, 5-HTP promotes emotional calm and relaxation in the evening hours, helping to ease the transition into restful sleep. It also plays a role in the body’s natural melatonin synthesis pathway.
Vitamin B6 (Pyridoxine) and Vitamin B2 (Riboflavin) — These two B vitamins work together to regulate circadian rhythm and support the body’s natural melatonin production. Vitamin B6 is also involved in the conversion of tryptophan to serotonin, making it an important cofactor for healthy sleep chemistry. Vitamin B2 has been associated with improved sleep quality and daytime alertness in clinical studies.
Magnesium Glycinate — Magnesium is one of the most important minerals for sleep. In its glycinate form, it is highly bioavailable and gentle on the stomach. Magnesium Glycinate promotes the deeper, restorative stages of sleep — the phases responsible for physical healing, memory consolidation, and hormonal balance. Many adults are deficient in magnesium, which directly contributes to light, fragmented sleep.
Apigenin — Often called “nature’s gentle sedative,” apigenin is a flavonoid found in chamomile and other botanicals. It binds to GABA receptors in the brain, helping to reduce the time it takes to fall asleep and decreasing the amount of time spent tossing and turning at bedtime. It promotes a calm, relaxed state without causing dependence or residual sedation the next morning.
Lemon Balm Extract — Lemon balm is a clinically studied herb that helps reduce cortisol — the stress hormone that spikes during the night when you’re under chronic stress. Elevated nighttime cortisol is one of the primary drivers of 3 AM wake-ups. By supporting healthy cortisol levels, Lemon Balm Extract helps you stay asleep through the night and wake up feeling calm rather than wired.
L-Theanine — L-Theanine is an amino acid naturally found in green tea that promotes alpha brain waves — the same relaxed, focused brainwave state associated with meditation. It reduces anxiety and racing thoughts without causing sedation, making it ideal for winding down an overactive mind at bedtime. When combined with GABA and Magnesium, its calming effects are significantly amplified.
Melatonin (0.9mg) — Rather than the standard 5mg or 10mg doses found in most sleep pills, Yu Sleep uses just 0.9mg of melatonin — a low, body-friendly amount that tells your brain it is time to rest. Research consistently shows that lower melatonin doses are just as effective for sleep onset while eliminating the morning grogginess and hormonal disruption associated with high-dose melatonin supplementation.
GABA (Gamma-Aminobutyric Acid) — GABA is the brain’s primary inhibitory neurotransmitter, responsible for quieting overactive neural circuits. When GABA activity is low, the brain remains in a state of hyperarousal — making it nearly impossible to fall asleep or stay asleep. Supplementing with GABA supports relaxation of the nervous system, reduces sleep latency, and promotes entry into deep, non-REM sleep stages.
Formula Synergy — What makes Yu Sleep especially effective is not any single ingredient but the way all 10 work together. Red Tart Cherry Extract and Vitamins B6 and B2 support natural melatonin production upstream. 5-HTP and Lemon Balm Extract address the serotonin and cortisol pathways. L-Theanine, GABA, and Apigenin calm the overactive nervous system. Magnesium Glycinate promotes the deeper sleep stages. And the precise 0.9mg melatonin dose provides the final circadian signal your brain needs to transition fully into restorative sleep. Together, these ingredients deliver a complete sleep system reset — night after night.